Tmem63a是什么
WebCatalog #. AM16708. Standard 5 nmol. Purification: HPLC In-Vivo Ready Standard. Size: 5 nmol 20 nmol 20 nmol 20 nmol 20 nmol 40 nmol 40 nmol 100 nmol 250 nmol 250 nmol 1 … WebTMEM63A is part of cluster 8 Oligodendrocytes - Myelin sheath organization with confidence i Confidence is the fraction of times a gene was assigned to the cluster in …
Tmem63a是什么
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WebIDG-HEK293T-TMEM63A-V5-OE. Selection: Blasticidin to a final concentration of 10μg/m. Organism: Homo sapiens, human. Description: This cell line stably expresses dark ion channel in frame with V5 tag on the C-terminus. The ion channel construct is randomly integrated in the genome using lentiviral transduction. This cell line also expresses ... WebJul 12, 2024 · TMEM63A is a newly-identified mechanosensitive ion channel. 75.6% ± 2.4% of Tmem63a + DRG neurons were IB4 + DRG neurons and 95.7% ± 1.7% of IB4 + DRG …
WebHuman diseases caused by Tmem63a mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER. Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes. Human diseases associated with … WebMar 30, 2024 · Monoallelic mutations on TMEM63A have been recently reported as cause of a previously unrecognized disorder named “infantile-onset transient hypomyelination”. Clinical and neuroradiological ...
WebDec 8, 2024 · Homologs of the TMEM63A gene: The TMEM63A gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog. Orthologs from Annotation Pipeline: 334 organisms have orthologs with human gene TMEM63A; Orthologs WebNov 21, 2024 · TMEM63A于2024年与髓鞘形成低下性脑白质营养不良19型（hypomyelinating leukodystrophy 19，HLD19）相关联，确定为HLD19的致病基因。 髓 …
WebKJ892838 - Synthetic construct Homo sapiens clone ccsbBroadEn_02232 TMEM63A gene, encodes complete protein. AB383993 - Synthetic construct DNA, clone: pF1KSDA0792, Homo sapiens TMEM63A gene for transmembrane protein 63A, complete cds, without stop codon, in Flexi system. AK093860 - Homo sapiens cDNA FLJ36541 fis, clone …
WebCRISPR/Cas9 KO Plasmids consists of TMEM63A-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library. For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB) in the genomic DNA. Target-specific CRISPR Plasmids for both gene knockout and activation are available. tracey harris murderWebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. TMEM63A INFORMATION. Proteini. Full gene name according to HGNC. Transmembrane protein … traceyharris541 gmail.comWebThis is a rabbit polyclonal antibody against TMEM63A and was validated on Western blot. Theoretical MW. 89 kDa. Disclaimer note: The observed molecular weight of the protein … tracey hartley avon ohhttp://www.pibb.ac.cn/pibbcn/article/html/20240421 tracey harshellWebStrikingly, TMEM63A in turn stabilizes oncoprotein DERL1 through preventing TOLLIP-mediated autophagic degradation. Notably, pharmacological inhibition of VCP by CB-5083 or knockdown of DERL1 partially abolishes the oncogenic effects of TMEM63A on TNBC progression both in vitro and in vivo. Collectively, these findings uncover a previously ... thermo vented stoveTransmembrane protein 63A is a protein that in humans is encoded by the TMEM63A gene. The mature human protein is approximately 92.1 kilodaltons (kDa), with a relatively high conservation of mass in orthologs. The protein contains eleven transmembrane domains and is inserted into the membrane of … See more Overview TMEM63A is located on the negative DNA strand of chromosome 1 at location 1q42.12, spanning base pairs 226,033,237 to 226,070,069. Aliases include KIAA0489 and KIAA0792. The … See more Properties and characteristics The mature form of the human TMEM63A protein has 807 amino acid residues with an isoelectric point of 6.925. This is fairly conserved across … See more • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): … See more Paralogs TMEM63A has two paralogs: TMEM63B, which is located at 6p21.1, and TMEM63C, which is located at C14orf171. Alignment between them shows that TMEM63C is more closely related to TMEM63B than TMEM63A. A BLAST … See more thermovent brushWebThe TMEM63A CRISPR guide RNA sequences shown above were designed by the laboratory of Feng Zhang at the Broad Institute* in order to efficiently target the TMEM63A gene with minimal risk of off-target Cas9 binding elsewhere in the genome. For complete details on the criteria and process for guide RNA design and selection, please see: Sanjana N ... tracey has a crush on harry fanfiction