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Web抗体-药物偶联物(ADC)是将细胞毒性小分子药物与单克隆抗体偶联的靶向抗肿瘤药物,利用抗体的特异靶向性和细胞毒性小分子的高效抗肿瘤活性,达到高效低毒的目的,是当前肿瘤创新药研发的热点。文章主要从单克隆抗体的筛选和人源化改造、靶点抗原的选择、细胞毒小分子的类型、连接子的偶联策略 ... http://professionalregistry.net/negative-options.html WebAug 8, 2015 · About Michael P. Sealy. Dr. Michael Sealy joined the University of Nebraska-Lincoln (UNL) in Lincoln, NE, USA as an Assistant Professor in 2015. His primary research field is advanced manufacturing of metals and food to solve problems in health. He investigates the role manufacturing processes have on process signature, surface … scotiabank money exchange rate