Web16 feb 2024 · The JCOG9912 trial based on which the JCOG index was constructed was a phase III study of the previous era and did not contain the modern S-1/platinum combinations. Nevertheless, the JCOG index served well as a prognostic indicator among patients who were treated by the state-of-the-art combination regimens that are currently … WebBackground: The best chemotherapy regimen for metastatic gastric cancer is uncertain, but promising findings have been reported with irinotecan plus cisplatin and S-1 (tegafur, 5 …
Fluorouracil versus combination of irinotecan plus cisplatin
WebBackground: Since the best chemotherapy regimen for each patient with advanced gastric cancer is uncertain, we aimed to identify molecular prognostic or predictive biomarkers from biopsy specimens in JCOG9912, a randomized phase III trial for advanced gastric cancer. Patients and methods: Endoscopic biopsy specimens from primary lesions were … Web22 mag 2015 · Abstract: Excision repair cross-complementary group 1 (ERCC1) is a significant protein in the nucleotide excision repair pathway. ERCC1 activity has been previously reported as a significant biomarker for the efficacy of platinum-based chemotherapy in some cancers such as lung, ovary, gastric and colorectal cancer. etheric vortex: gloomtide shipwreck
Impact of excision repair cross-complementing gene 1 (ERCC1) on …
WebTable II . The JCOG9912 and JCOG0106 trials were conducted during the period of our analysis and 30% of the patients at TCC were also enrolled in those trials. The median survival time was 11.7 months and the median follow-up period of the survivors was 17.5 months (range, 1.4-43 months). Complications. As determined by our diagnostic criteria, the Web1 feb 2016 · PDF Background The standard chemotherapy regimen for gastric cancer has been established by several phase III trials. However, few studies have... Find, read and cite all the research you need ... Web26 ott 2013 · Background Two randomized phase III trials of first-line chemotherapy for advanced gastric cancer (JCOG9205 and JCOG9912) conducted by the Japan Clinical … etheric vitality